Impact of Phase Analysis of Gated SPECT to Assessment of Left Ventricular Mechanical Dyssynchrony in Diabetic Patients with Normal MPI
Authors
Abstract:
Objective: Diabetes mellitus is an important cause of heart failure deployment of left ventricular mechanical dyssynchrony. Nuclear cardiology phase analysis is an accurate, repeatable and reproducible modality for measurement LV dyssynchrony .The aim of study was assessment of phase analysis parameter including Standard deviation (SD) and band width (BW) in diabetic patient with normal MPI comparing with low risk population for CHD. Materials and Methods: An analytical cross-sectional study was performed in clinical research development unit of Farshchian heart center, Hamedan University of Medical Sciences. We evaluated 165 patients who underwent SPECT MPI. Study population were 90 diabetic patients with normal MPI (sss<3) and 75 health individuals without diabetes. Phase analysis parameters were compared in both groups using Quantitative Gated SPECT (QGS) software. Independent sample t-test and Pearson correlation test were used to compare the results. Results: The study results revealed no statistically significant differences in standard deviation (SD) and histogram band width (BW) of the phase analysis between diabetic patients and control group. Furthermore, in diabetic patient LVEF have a negative significant correlation to BW (r=-0.510) and SD (r=-0.422) but in control group there was no significant Pearson correlation is noticed. Conclusion: Between diabetic patients and low likelihood person for CHD with normal MPI phase analysis parameter (BW and SD) shows no significant difference.
similar resources
Evaluation of the potential impact of reconstruction method on dyssynchrony parameters derived by phase analysis of gated-SPECT MPI: Comparison of two quantitative software
Introduction: Gated SPECT myocardial perfusion scanning has new capabilities in addition to its main applications such as left ventricular dyssynchrony using phase analysis. Phase analysis has been investigated through various software including Emory Cardiac Toolbox (ECTb) and Quantitative Gated SPECT (QGS). The aim of this study is to evaluate the effect of reconstruction par...
full textNormal values of left ventricular functional indices in gated 99mTc-MIBI myocardial perfusion SPECT
Introduction: Although left ventricular(LV) function parameters measured by gated myocardial perfusion SPECT (GSPECT) have been validated, experimental data have revealed that the calculated the LV function parameters using GSPECT are affected by patient populations as well as particular acquisition and processing conditions. We tried to determine the normal values ...
full textLeft ventricular mechanical dyssynchrony in patients with impaired left ventricular function undergoing gated SPECT myocardial perfusion imaging.
INTRODUCTION Gated SPECT myocardial perfusion imaging (MPI) has been used to quantify mechanical dyssynchrony. Mechanical dyssynchrony appears to be related to response to cardiac resynchronization therapy. OBJECTIVE To evaluate the presence and predictors of mechanical dyssynchrony in patients with impaired left ventricular function (LVEF) ≤50%. METHODS The study included 143 consecutive p...
full textDetermination of normal ranges of regional and global phase parameters using gated myocardial perfusion imaging with Cedars-Sinai’s QGS software
Introduction: Myocardial perfusion imaging using gated SPECT and phase analysis is an effective tool in evaluation of mechanical dyssynchrony. The purpose of this study was to determine the normal ranges of global and regional phase parameters. Methods: A total of 100 patients with normal resting and stress electrocardiograms, low pretest likelihood for c...
full textMy Resources
Journal title
volume 9 issue 3
pages 117- 120
publication date 2017-09
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023